Grant NCN MINIATURA na badania bioaktywnych powłok poprawiających właściwości implantów kości

Polymer implants may be used for the reconstruction, stabilization, or filling of extensive bone defects resulting from trauma or disease. However, due to their bioinert nature, they often exhibit limited osseointegration with the surrounding bone tissue. Therefore, the development of bioactive coatings, particularly those based on nanohydroxyapatite (nHAP), is essential to support bone regeneration.

Dr. Urszula Szałaj from the Laboratory of Nanostructures (NL4) from our Institute will carry out a MINIATURA project “Nanoarchitektura bioaktywnych powłok HAP na implantach PEEK: badania wstępne zależności między powierzchnią właściwą nanocząstek, stabilnością warstwy i profilem uwalniania jonów Ca²⁺” funded by National Science Center (NCN). She will search for the answer not only whether the hydroxyapatite coating is effective, but above all, which parameters of its nanoarchitecture determine the stability and function of the layer. We want to determine the relationships between the size and active surface area of the nanoparticles, the coating architecture, and the Ca²⁺ release profile, which will enable us to identify the variants with the highest potential for further biological studies.

The announcement of the competition results and the list of funded projects for MINIATURA 10 edition can be found on the National Science Center’s website.